Fibrosis in Human Adipose Tissue: Composition, Distribution, and Link With Lipid Metabolism and Fat Mass Loss

Fibrosis is a newly appreciated hallmark of the pathological alteration of human white adipose tissue (WAT). We investigated the composition of subcutaneous (scWAT) and omental WAT (oWAT) fibrosis in obesity and its relationship with metabolic alterations and surgery-induced weight loss. Surgical bi...

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Veröffentlicht in:	Diabetes (New York, N.Y.) N.Y.), 2010-11, Vol.59 (11), p.2817-2825
Hauptverfasser:	DIVOUX, Adeline, TORDJMAN, Joan, BEDOSSA, Pierre, CLEMENT, Karine, LACASA, Danièle, VEYRIE, Nicolas, HUGOL, Danielle, AISSAT, Abdelhalim, BASDEVANT, Arnaud, GUERRE-MILLO, Michèle, POITOU, Christine, ZUCKER, Jean-Daniel
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose tissue Adipose Tissue - metabolism Adipose Tissue - pathology Adipose Tissue, White - metabolism Adipose Tissue, White - pathology Adipose tissues Azo Compounds - metabolism Bariatric surgery Biological and medical sciences Biopsy Body Composition Body fat Collagen Collagen - metabolism Collagen Type VI - metabolism Diabetes Diabetes mellitus Diabetes. Impaired glucose tolerance Endocrine pancreas. Apud cells (diseases) Endocrinology and metabolism Endocrinopathies Etiopathogenesis. Screening. Investigations. Target tissue resistance Female Fibrosis Fibrosis - metabolism Fibrosis - pathology Food and Nutrition Gastrointestinal surgery Human health and pathology Humans Immunohistochemistry Insulin resistance Life Sciences Lipid Metabolism Macrophages Male Medical sciences Obesity Obesity - metabolism Obesity - pathology Obesity Studies Obesity, Morbid - metabolism Obesity, Morbid - pathology Omentum - metabolism Omentum - pathology Physiological aspects Polymerase Chain Reaction - methods Surgery Surgical Procedures, Operative - methods Thinness - genetics Thinness - metabolism Triglycerides
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