Indication for a role of regulatory T cells for the advent of influenza A (H1N1)-related pneumonia

Regulatory T cells (Tregs) have an anti-inflammatory role. A former study in a limited number of patients found that absolute counts of Tregs increase when infection by the new influenza H1N1 virus is complicated with pneumonia. These results generate the question if H1N1-related pneumonia is associ...

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Veröffentlicht in:	Clinical and experimental immunology 2010-09, Vol.161 (3), p.576-583
Hauptverfasser:	Raftogiannis, M, Antonopoulou, A, Baziaka, F, Spyridaki, A, Koutoukas, P, Tsaganos, T, Savva, A, Pistiki, A, Georgitsi, M, Giamarellos-Bourboulis, E.J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Blood CD14 antigen cytokines Enzyme immunoassay Female Flow Cytometry H1N1 influenza Histocompatibility antigen HLA HLA-DR Antigens - metabolism Humans Immunophenotyping Immunoregulation Infection Inflammation Influenza A Influenza A Virus, H1N1 Subtype - immunology Influenza, Human - blood Influenza, Human - complications Influenza, Human - immunology Interleukin 10 Interleukin-6 - blood Leukocytes Lipopolysaccharide Receptors - metabolism Lymphocytes T Male Membrane Glycoproteins - blood Middle Aged Monocytes Pneumonia Pneumonia, Bacterial - blood Pneumonia, Bacterial - complications Pneumonia, Bacterial - immunology procalcitonin Receptors, Immunologic - blood Regression analysis regulatory T cells Sampling T-Lymphocytes, Regulatory - immunology T-Lymphocytes, Regulatory - metabolism Translational Studies Triggering Receptor Expressed on Myeloid Cells-1 Tumor necrosis factor-a Tumor Necrosis Factor-alpha - blood Young Adult
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