Glucocorticoid receptor beta, a potential endogenous inhibitor of glucocorticoid action in humans

Alternative splicing of the human glucocorticoid receptor (hGR) pre-mRNA generates two highly homologous isoforms, termed hGR alpha and hGR beta. hGR alpha is a ligand-activated transcription factor which, in the hormone-bound state, modulates the expression of glucocorticoid-responsive genes by bin...

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Veröffentlicht in:	The Journal of clinical investigation 1995-06, Vol.95 (6), p.2435-2441
Hauptverfasser:	Bamberger, C M, Bamberger, A M, de Castro, M, Chrousos, G P
Format:	Artikel
Sprache:	eng
Schlagworte:	Alternative Splicing Animals Base Sequence Cells, Cultured Cercopithecus aethiops Dexamethasone - metabolism DNA Primers - chemistry DNA-Binding Proteins - metabolism Gene Expression Glucocorticoids - antagonists & inhibitors Humans In Vitro Techniques Molecular Sequence Data Receptors, Glucocorticoid - physiology Recombinant Proteins Regulatory Sequences, Nucleic Acid RNA, Messenger - genetics Transcription, Genetic
Online-Zugang:	Volltext
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