A direct comparison of strategies for combinatorial RNA interference

Combinatorial RNA interference (co-RNAi) is a valuable tool for highly effective gene suppression of single and multiple-genes targets, and can be used to prevent the escape of mutation-prone transcripts. There are currently three main approaches used to achieve co-RNAi in animal cells; multiple pro...

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Veröffentlicht in:	BMC molecular biology 2010-10, Vol.11 (1), p.77-77, Article 77
Hauptverfasser:	Lambeth, Luke S, Van Hateren, Nick J, Wilson, Stuart A, Nair, Venugopal
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Animals Base Sequence Cell Line Cells Chick Embryo Cloning Competition Deoxyribonucleic acid Design DNA Gene expression Gene Knockdown Techniques - methods Genes Genetic vectors Genetic Vectors - genetics Methodology Methods MicroRNA MicroRNAs - genetics Molecular Sequence Data Plasmids Plasmids - genetics Promoter Regions, Genetic Retroviridae - genetics Ribonucleic acid RNA RNA Interference RNA, Small Interfering - administration & dosage RNA, Small Interfering - genetics Studies
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