Electrophysiological classification of P2X7 receptors in rat cultured neocortical astroglia

Background and purpose: P2X7 receptors are ATP‐gated cation channels mediating important functions in microglial cells, such as the release of cytokines and phagocytosis. Electrophysiological evidence that these receptors also occur in CNS astroglia is rare and rather incomplete. Experimental appro...

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Veröffentlicht in:	British journal of pharmacology 2010-08, Vol.160 (8), p.1941-1952
Hauptverfasser:	Nörenberg, W, Schunk, J, Fischer, W, Sobottka, H, Riedel, T, Oliveira, JF, Franke, H, Illes, P
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - metabolism Animals astrocytes Astrocytes - drug effects Astrocytes - metabolism astroglia Biological and medical sciences Brain Cells, Cultured Coculture Techniques extracellular ATP glial necrosis glial proliferation Immunohistochemistry Medical sciences Membrane Potentials Membrane Transport Modulators - pharmacology Neocortex - drug effects Neocortex - embryology Neocortex - metabolism Neurons - metabolism P2X7 receptors Patch-Clamp Techniques Pharmacology. Drug treatments Purinergic P2 Receptor Agonists Purinergic P2 Receptor Antagonists Rats Rats, Wistar Receptors, Purinergic P2 - metabolism Receptors, Purinergic P2X7 Research Papers Rodents
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