Osteonectin/SPARC Secreted by RPE and Localized to the Outer Plexiform Layer of the Monkey Retina

Osteonectin/SPARC is a secreted protein that has been implicated in ocular disease. Deletion of osteonectin/SPARC causes age-onset cataract in mice and the cataractous human lens has increased expression of osteonectin/SPARC. In this study, the expression and localization of osteonectin/SPARC in the...

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Veröffentlicht in:	Investigative ophthalmology & visual science 2000-08, Vol.41 (9), p.2438-2444
Hauptverfasser:	Rodriguez, Ignacio R, Moreira, Ernesto F, Bok, Dean, Kantorow, Marc
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Biological Transport - physiology Blotting, Northern Blotting, Western Cells, Cultured DNA Primers - chemistry Electrophoresis, Polyacrylamide Gel Eye and associated structures. Visual pathways and centers. Vision Eye Proteins - genetics Eye Proteins - metabolism Fundamental and applied biological sciences. Psychology Immunoenzyme Techniques Macaca mulatta Osteonectin - genetics Osteonectin - metabolism Pigment Epithelium of Eye - cytology Pigment Epithelium of Eye - metabolism Retina - metabolism RNA, Messenger - metabolism Subcellular Fractions Vertebrates: nervous system and sense organs
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