TRPC6 channels and their binding partners in podocytes: role in glomerular filtration and pathophysiology

Loss or dysfunction of podocytes is a major cause of glomerular kidney disease. Several genetic forms of glomerular disease are caused by mutations in genes that encode structural elements of the slit diaphragm or the underlying cytoskeleton of podocyte foot processes. The recent discovery that gain...

Ausführliche Beschreibung