Analysis of ionizing radiation-induced DNA damage and repair in three-dimensional human skin model system

Please cite this paper as: Analysis of ionizing radiation‐induced DNA damage and repair in three‐dimensional human skin model system. Experimental Dermatology 2010; 19: e16–e22. : Knowledge of cellular responses in tissue microenvironment is crucial for the accurate prediction of human health risks...

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Veröffentlicht in:	Experimental dermatology 2010-08, Vol.19 (8), p.e16-e22
Hauptverfasser:	Su, Yanrong, Meador, Jarah A., Geard, Charles R., Balajee, Adayabalam S.
Format:	Artikel
Sprache:	eng
Schlagworte:	53 binding protein 1 Biomarkers - metabolism Cell Line Chromones - pharmacology DNA Breaks, Double-Stranded - drug effects DNA Breaks, Double-Stranded - radiation effects DNA Damage - drug effects DNA Damage - radiation effects DNA Repair - drug effects DNA Repair - radiation effects Dose-Response Relationship, Radiation double strand break induction and repair Enzyme Inhibitors - pharmacology EpiDerm tissue constructs Fibroblasts - drug effects Fibroblasts - metabolism Fibroblasts - radiation effects Gamma Rays - adverse effects Humans Intracellular Signaling Peptides and Proteins - metabolism low LET radiation Models, Biological Morpholines - pharmacology Phosphatidylinositol 3-Kinases - metabolism phosphatidylinositol-3 kinase like kinases Radiation, Ionizing Signal Transduction - drug effects Signal Transduction - radiation effects Skin - drug effects Skin - metabolism Skin - radiation effects Tumor Suppressor p53-Binding Protein 1
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