Uridine supplementation in the treatment of HIV lipoatrophy: results of ACTG 5229

Lipoatrophy is prevalent on thymidine nucleoside reverse transcriptase inhibitors (tNRTIs). A pilot trial showed that uridine (NucleomaxX) increased limb fat. A5229 was a multicenter trial in which HIV-infected individuals with lipoatrophy on tNRTI regimens were randomized to NucleomaxX or placebo....

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Veröffentlicht in:	AIDS (London) 2010-10, Vol.24 (16), p.2507-2515
Hauptverfasser:	MCCOMSEY, Grace A, WALKER, Ulrich A, BUDHATHOKI, Chakra B, ZHAOHUI SU, CURRIER, Judith S, KOSMISKI, Lisa, NAINI, Linda G, CHARLES, Stéphannie, MEDVIK, Kathy, ABERG, Judith A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences CD4 Lymphocyte Count Dermatology Double-Blind Method Drug toxicity and drugs side effects treatment Female HIV Infections - complications HIV Infections - drug therapy HIV Infections - virology HIV-1 HIV-Associated Lipodystrophy Syndrome - chemically induced HIV-Associated Lipodystrophy Syndrome - drug therapy HIV-Associated Lipodystrophy Syndrome - virology Human immunodeficiency virus 1 Human viral diseases Humans Infectious diseases Male Medical sciences Medication Adherence - statistics & numerical data Miscellaneous (drug allergy, mutagens, teratogens...) Pharmacology. Drug treatments Pilot Projects Quality of Life Skin involvement in other diseases. Miscellaneous. General aspects Uridine - therapeutic use Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids Viral Load
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