The solution structure of the ADAR2 dsRBM-RNA complex reveals a sequence-specific read out of the RNA minor groove

Sequence-dependent recognition of dsDNA-binding proteins are well understood, yet sequence-specific recognition of dsRNA by proteins remains largely unknown, despite their importance in RNA maturation pathways. Adenosine deaminases that act on RNA (ADARs) recode genomic information by the site-selec...

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Veröffentlicht in:Cell 2010-10, Vol.143 (2), p.225-237
Hauptverfasser: Stefl, Richard, Oberstrass, Florian C., Hood, Jennifer L., Jourdan, Muriel, Zimmermann, Michal, Skrisovska, Lenka, Maris, Christophe, Peng, Li, Hofr, Ctirad, Emeson, Ronald B., Allain, Frédéric H.-T.
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Sprache:eng
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