The role of complement in experimental bullous pemphigoid

Bullous pemphigoid (BP) is a blistering skin disease associated with an IgG autoimmune response directed against the ectodomain of the hemidesmosomal protein, BP180. An animal model of BP has recently been developed by our laboratory based on the passive transfer of rabbit antimurine BP180 antibodie...

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Veröffentlicht in:	The Journal of clinical investigation 1995-04, Vol.95 (4), p.1539-1544
Hauptverfasser:	Liu, Z, Giudice, G J, Swartz, S J, Fairley, J A, Till, G O, Troy, J L, Diaz, L A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Autoantigens - immunology Blister - etiology Collagen Type XVII Complement Activation Complement C5 - genetics Complement C5 - metabolism Disease Models, Animal Immunoglobulin Fab Fragments - immunology Immunoglobulin Fab Fragments - isolation & purification Immunoglobulin G - immunology Immunoglobulin G - isolation & purification Mice Mice, Inbred BALB C Mice, Mutant Strains Non-Fibrillar Collagens Pemphigoid, Bullous - etiology Pemphigoid, Bullous - immunology Skin - pathology
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