Angiogenesis and Breast Cancer

Angiogenesis and Breast Cancer

Angiogenesis is an essential step for breast cancer progression and dissemination. The development of new blood vessels in cancer setting (angiogenesis) is conducted by numerous physiological and pathological stimuli, where the main stimulus is hypoxia. The knowledge of different molecular pathways...

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Veröffentlicht in:Journal of oncology 2010-01, Vol.2010 (2010), p.1-7
Hauptverfasser: Longatto Filho, Adhemar, Lopes, José Manuel, Schmitt, Fernando C.
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Sprache:eng
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Review
Science & Technology
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container_issue 2010
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container_title Journal of oncology
container_volume 2010
creator Longatto Filho, Adhemar
Lopes, José Manuel
Schmitt, Fernando C.
description Angiogenesis is an essential step for breast cancer progression and dissemination. The development of new blood vessels in cancer setting (angiogenesis) is conducted by numerous physiological and pathological stimuli, where the main stimulus is hypoxia. The knowledge of different molecular pathways regulating angiogenesis is constantly growing. An increased and complex scenario of angiogenesis is nowadays available in breast cancer, specifically, and permits not only to understand most of the important phases of neoplastic growth but also offer an exciting perspective for new therapeutic proposals based on blocking new blood vessels sprouting. This review focused on historical and recent understanding of angiogenesis occurrence in breast cancer.
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subjects Review
Science & Technology
title Angiogenesis and Breast Cancer
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