Berberine Moderates Glucose and Lipid Metabolism through Multipathway Mechanism

Berberine is known to improve glucose and lipid metabolism disorders, but the mechanism is still under investigation. In this paper, we explored the effects of berberine on the weight, glucose levels, lipid metabolism, and serum insulin of KKAy mice and investigated its possible glucose and lipid-re...

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Veröffentlicht in:	Evidence-based complementary and alternative medicine 2011-01, Vol.2011 (2011), p.1-10
Hauptverfasser:	Zhang, Qian, Xiao, Xin-Hua, Feng, Kai, Wang, Tong, Li, Wenhui, Yuan, Tao, Sun, Xiaofang, Sun, Qi, Xiang, Hongding, Wang, Heng
Format:	Artikel
Sprache:	eng
Schlagworte:	AMP AMP-activated protein kinase Berberine Blood glucose c-Jun protein CCAAT/enhancer-binding protein Cholesterol Diabetes Enzymes Fasting Fins Gene expression Genes Glucose Glucose metabolism Glucose tolerance Glucose transporter High density lipoprotein Homeostasis Hyperglycemia Insulin Insulin resistance JNK protein Lipid metabolism Lipids Liver Low density lipoprotein MAP kinase Metabolism Mice Mitochondrial uncoupling protein 2 Muscles Musculoskeletal system Obesity Peroxisome proliferator-activated receptors Pharmaceuticals Proteins Skeletal muscle Transcription factors Veins & arteries Weight control
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