Neutrophil nicotinamide adenine dinucleotide phosphate oxidase assembly : translocation of p47-phox and p67-phox requires interaction between p47-phox cytochrome b558

Two of the cytosolic NADPH oxidase components, p47-phox and p67-phox, translocate to the plasma membrane in normal neutrophils stimulated with phorbol myristate acetate (PMA). We have now studied the translocation process in neutrophils of patients with chronic granulomatous disease (CGD), an inheri...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	The Journal of clinical investigation 1991, Vol.87 (1), p.352-356
Hauptverfasser:	HEYWORTH, P. G, CURNUTTE, J. T, NAUSEEF, W. M, VOLPP, B. D, PEARSON, D. W, ROSEN, H, CLARK, R. A
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Biological Transport Cytochrome b Group - physiology Granulomatous Disease, Chronic - enzymology Humans Medical sciences NADH, NADPH Oxidoreductases - analysis NADH, NADPH Oxidoreductases - metabolism NADPH Oxidases Neutrophils - enzymology Phosphorylation Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!