Interferon-inducible p200-family proteins as novel sensors of cytoplasmic DNA: role in inflammation and autoimmunity

Deregulated innate immune responses that result in increased levels of type I interferons (IFNs) and stimulation of IFN-inducible genes are thought to contribute to chronic inflammation and autoimmunity. One family of IFN-inducible genes is the Ifi200 family, which includes the murine (eg, Ifi202a,...

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Veröffentlicht in:	Journal of interferon & cytokine research 2010-06, Vol.30 (6), p.371-380
Hauptverfasser:	Choubey, Divaker, Duan, Xin, Dickerson, Eric, Ponomareva, Larissa, Panchanathan, Ravichandran, Shen, Hui, Srivastava, Ratika
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Autoimmunity Chronic diseases Disease Models, Animal DNA-Binding Proteins - immunology Female Genetic aspects Health aspects Humans Immune response Inflammation Interferon Mice Nuclear Proteins - immunology Reviews Risk factors
Online-Zugang:	Volltext
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