Bone and glucose metabolism: A two-way street

Evidence from rodent models indicates that undercarboxylated osteocalcin (ucOC), a product of osteoblasts, is a hormone affecting insulin production by the pancreas and insulin sensitivity in peripheral tissues, at least in part through enhanced secretion of adiponectin from adipocytes. Clinical res...

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Veröffentlicht in:	Archives of biochemistry and biophysics 2010-11, Vol.503 (1), p.2-10
Hauptverfasser:	Motyl, Katherine J., McCabe, Laura R., Schwartz, Ann V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bone and Bones - drug effects Bone and Bones - metabolism Bone and Bones - physiopathology Diabetes Mellitus - drug therapy Diabetes Mellitus - metabolism Diabetes Mellitus - physiopathology Glucose - metabolism Humans Insulin sensitivity Models, Animal Osteocalcin - metabolism Undercarboxylated osteocalcin
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