Localized 1H-NMR spectroscopy in patients with fibromyalgia: a controlled study of changes in cerebral glutamate/glutamine, inositol, choline, and N-acetylaspartate

The purpose of this study was to investigate whether single-voxel (SV) proton magnetic resonance spectroscopy (MRS), diffusion-weighted imaging (DWI), and diffusion tensor imaging (DTI) detected differences between fibromyalgia (FM) patients and healthy controls. We also searched for correlations be...

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Veröffentlicht in:	Arthritis research & therapy 2010-01, Vol.12 (4), p.R134-R134, Article R134
Hauptverfasser:	Fayed, Nicolas, Garcia-Campayo, Javier, Magallón, Rosa, Andrés-Bergareche, Helena, Luciano, Juan V, Andres, Eva, Beltrán, Julián
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aspartic Acid - analogs & derivatives Aspartic Acid - metabolism Brain - metabolism Brain - pathology Cholic Acid - metabolism Cross-Sectional Studies Diffusion Tensor Imaging Female Fibromyalgia - metabolism Fibromyalgia - pathology Glutamic Acid - metabolism Glutamine - metabolism Hippocampus - metabolism Hippocampus - pathology Humans Inositol - metabolism Male Middle Aged Motor Cortex - metabolism Motor Cortex - pathology Nuclear Magnetic Resonance, Biomolecular Pain - metabolism Pain - pathology Protons Somatosensory Cortex - metabolism Somatosensory Cortex - pathology
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