Functional basis for complement evasion by staphylococcal superantigen-like 7

The human pathogen Staphylococcus aureus has a plethora of virulence factors that promote its colonization and survival in the host. Among such immune modulators are staphylococcal superantigen-like (SSL) proteins, comprising a family of 14 small, secreted molecules that seem to interfere with the h...

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Veröffentlicht in:	Cellular microbiology 2010-10, Vol.12 (10), p.1506-1516
Hauptverfasser:	Bestebroer, Jovanka, Aerts, Piet C, Rooijakkers, Suzan H.M, Pandey, Manoj K, Köhl, Jörg, van Strijp, Jos A.G, de Haas, Carla J.C
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models Animals Antigen-antibody complexes Blood Blood - immunology Colonization Complement activation Complement C5a - immunology complement component C5 complement component C5a Disease Models, Animal Escherichia coli Exotoxins - immunology Humans Immune Evasion Immune system Immunoglobulin A Immunomodulation Inflammation Leukocytes (neutrophilic) Mice Mice, Inbred BALB C Opsonization Pathogens Peritoneum Peritonitis Peritonitis - immunology Peritonitis - microbiology Phagocytosis Staphylococcal Infections - immunology Staphylococcal Infections - microbiology Staphylococcus aureus Staphylococcus aureus - immunology Staphylococcus aureus - pathogenicity virulence factors
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