The nonphagocytic NADPH oxidase Duox1 mediates a positive feedback loop during T cell receptor signaling

Production of reactive oxygen species, often by NADPH (reduced form of nicotinamide adenine dinucleotide phosphate) oxidases, plays a role in the signaling responses of cells to many receptor stimuli. Here, we describe the function of the calcium-dependent, nonphagocytic NADPH oxidase Duox1 in prima...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Science signaling 2010-08, Vol.3 (133), p.ra59-ra59
Hauptverfasser:	Kwon, Jaeyul, Shatynski, Kristen E, Chen, Haiyan, Morand, Stanislas, de Deken, Xavier, Miot, Françoise, Leto, Thomas L, Williams, Mark S
Format:	Artikel
Sprache:	eng
Schlagworte:	Calcium - metabolism Cells, Cultured Dual Oxidases Feedback, Physiological Humans Hydrogen Peroxide - metabolism NADPH Oxidases - immunology Receptors, Antigen, T-Cell - metabolism Signal Transduction T-Lymphocytes - cytology T-Lymphocytes - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!