Hyperpolarized 13C magnetic resonance metabolic imaging: application to brain tumors

In order to compare in vivo metabolism between malignant gliomas and normal brain, (13)C magnetic resonance (MR) spectroscopic imaging data were acquired from rats with human glioblastoma xenografts (U-251 MG and U-87 MG) and normal rats, following injection of hyperpolarized [1-(13)C]-pyruvate. The...

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Veröffentlicht in:	Neuro-oncology (Charlottesville, Va.) Va.), 2010-02, Vol.12 (2), p.133-144
Hauptverfasser:	Park, Ilwoo, Larson, Peder E Z, Zierhut, Matthew L, Hu, Simon, Bok, Robert, Ozawa, Tomoko, Kurhanewicz, John, Vigneron, Daniel B, Vandenberg, Scott R, James, C David, Nelson, Sarah J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Basic and Translational Investigations Brain Neoplasms - diagnosis Brain Neoplasms - metabolism Carbon Radioisotopes Humans Immunohistochemistry Magnetic Resonance Spectroscopy - methods Male Neoplasms, Experimental - diagnosis Neoplasms, Experimental - metabolism Radiopharmaceuticals Rats Rats, Nude Transplantation, Heterologous
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