Tgif1 represses apolipoprotein gene expression in liver

TG‐interacting factor (Tgif1) represses gene expression by interaction with general corepressors, and can be recruited to target genes by transforming growth factor beta (TGFβ) activated Smads, or by the retinoid X receptor (RXR). Here we show that Tgif1 interacts with the LXRα nuclear receptor and...

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Veröffentlicht in:	Journal of cellular biochemistry 2010-10, Vol.111 (2), p.380-390
Hauptverfasser:	Melhuish, Tiffany A., Chung, David D., Bjerke, Glen A., Wotton, David
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals apolipoprotein Apolipoprotein C-II - analysis Apolipoprotein C-II - genetics Apolipoproteins - analysis Apolipoproteins - genetics Apolipoproteins A - analysis Apolipoproteins A - genetics Gene Expression Regulation Homeodomain Proteins - physiology Liver - metabolism Liver X Receptors LXR Mice Orphan Nuclear Receptors Receptors, Cytoplasmic and Nuclear - metabolism repressor Repressor Proteins - physiology Tgif transcription
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