Cost-effectiveness of colorectal cancer screening – An overview

There are several modalities available for a colorectal cancer (CRC) screening program. When determining which CRC screening program to implement, the costs of such programs should be considered in comparison to the health benefits they are expected to provide. Cost-effectiveness analysis provides a...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Baillière's best practice & research. Clinical gastroenterology 2010-08, Vol.24 (4), p.439-449
Hauptverfasser: Lansdorp-Vogelaar, Iris, PhD, Knudsen, Amy B., PhD, Brenner, Hermann, MD, MPH
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 449
container_issue 4
container_start_page 439
container_title Baillière's best practice & research. Clinical gastroenterology
container_volume 24
creator Lansdorp-Vogelaar, Iris, PhD
Knudsen, Amy B., PhD
Brenner, Hermann, MD, MPH
description There are several modalities available for a colorectal cancer (CRC) screening program. When determining which CRC screening program to implement, the costs of such programs should be considered in comparison to the health benefits they are expected to provide. Cost-effectiveness analysis provides a tool to do this. In this paper we review the evidence on the cost-effectiveness of CRC screening. Published studies universally indicate that when compared with no CRC screening, all screening modalities provide additional years of life at a cost that is deemed acceptable by most industrialized nations. Many recent studies even find CRC screening to be cost-saving. However, when the alternative CRC screening strategies are compared against each other in an incremental cost-effectiveness analysis, no single optimal strategy emerges across the studies. There is consensus that the new technologies of stool DNA testing, computed tomographic colonography and capsule endoscopy are not yet cost-effective compared with the established CRC screening tests.
doi_str_mv 10.1016/j.bpg.2010.04.004
format Article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2939039</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>1_s2_0_S1521691810000582</els_id><sourcerecordid>754005150</sourcerecordid><originalsourceid>FETCH-LOGICAL-c599t-b9be88eccd5453b7f245eb42b50ae519f6d6617592bde8c2d6be148c15d3678f3</originalsourceid><addsrcrecordid>eNp9Ustu1DAUjRCIlsIHsEGRWLDKcP1KbCFVGo0oIFViAayvEudm8JCxBzszVXf8A3_YL8HRlAJdsPLrnCOfe05RPGewYMDq15tFt1svOOQzyAWAfFCcMiV4xQyrH857zqraMH1SPElpA5BJxjwuTjhoIYTUp8VyFdJU0TCQndyBPKVUhqG0YQwxX7VjaVtvKZbJRiLv_Lq8-fGzXPoyHCgeHF09LR4N7Zjo2e16Vny5ePt59b66_Pjuw2p5WVllzFR1piOtydpeSSW6ZuBSUSd5p6AlxcxQ93XNGmV415O2vK87YlJbpnpRN3oQZ8X5UXe377bUW_JTbEfcRbdt4zWG1uG_L959xXU4IDfCgDBZ4NWtQAzf95Qm3LpkaRxbT2GfsFESQDEFGfnyHnIT9tFnd8hA8EYarnlGsSPKxpBSpOHuLwxwzgc3mPPBOR8EiTmfzHnxt4k7xu9AMuDNEUB5lHm8EZN1lBPo3ZwH9sH9V_78HtuOzjvbjt_omtIfF5g4An6aCzL3g-VqgMqefgFDO7Zr</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1032749282</pqid></control><display><type>article</type><title>Cost-effectiveness of colorectal cancer screening – An overview</title><source>MEDLINE</source><source>ScienceDirect Journals (5 years ago - present)</source><creator>Lansdorp-Vogelaar, Iris, PhD ; Knudsen, Amy B., PhD ; Brenner, Hermann, MD, MPH</creator><creatorcontrib>Lansdorp-Vogelaar, Iris, PhD ; Knudsen, Amy B., PhD ; Brenner, Hermann, MD, MPH</creatorcontrib><description>There are several modalities available for a colorectal cancer (CRC) screening program. When determining which CRC screening program to implement, the costs of such programs should be considered in comparison to the health benefits they are expected to provide. Cost-effectiveness analysis provides a tool to do this. In this paper we review the evidence on the cost-effectiveness of CRC screening. Published studies universally indicate that when compared with no CRC screening, all screening modalities provide additional years of life at a cost that is deemed acceptable by most industrialized nations. Many recent studies even find CRC screening to be cost-saving. However, when the alternative CRC screening strategies are compared against each other in an incremental cost-effectiveness analysis, no single optimal strategy emerges across the studies. There is consensus that the new technologies of stool DNA testing, computed tomographic colonography and capsule endoscopy are not yet cost-effective compared with the established CRC screening tests.</description><identifier>ISSN: 1521-6918</identifier><identifier>EISSN: 1532-1916</identifier><identifier>DOI: 10.1016/j.bpg.2010.04.004</identifier><identifier>PMID: 20833348</identifier><identifier>CODEN: BPRCB6</identifier><language>eng</language><publisher>Netherlands: Elsevier Ltd</publisher><subject>Capsule endoscopy ; Capsule Endoscopy - economics ; Colonography, Computed tomographic ; Colonography, Computed Tomographic - economics ; Colonoscopy ; Colonoscopy - economics ; Colorectal cancer ; Colorectal neoplasms ; Colorectal Neoplasms - diagnosis ; Colorectal Neoplasms - economics ; Colorectal Neoplasms - prevention &amp; control ; Cost reduction ; Cost-benefit analysis ; Cost-Benefit Analysis - statistics &amp; numerical data ; Cost-Benefit Analysis - trends ; Deoxyribonucleic acid ; DNA ; Early Detection of Cancer - economics ; Early Detection of Cancer - statistics &amp; numerical data ; Early Detection of Cancer - trends ; Feces ; Female ; Gastroenterology and Hepatology ; Genetic testing ; Humans ; Intervention ; Male ; Mass screening ; Mass Screening - economics ; Mass Screening - methods ; Mass Screening - trends ; Mathematical models ; Medical screening ; Occult Blood ; Quality standards ; Quality-Adjusted Life Years ; Sigmoidoscopy ; Sigmoidoscopy - economics ; Stool DNA ; Studies</subject><ispartof>Baillière's best practice &amp; research. Clinical gastroenterology, 2010-08, Vol.24 (4), p.439-449</ispartof><rights>Elsevier Ltd</rights><rights>2010 Elsevier Ltd</rights><rights>Copyright © 2010 Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c599t-b9be88eccd5453b7f245eb42b50ae519f6d6617592bde8c2d6be148c15d3678f3</citedby><cites>FETCH-LOGICAL-c599t-b9be88eccd5453b7f245eb42b50ae519f6d6617592bde8c2d6be148c15d3678f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.bpg.2010.04.004$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>230,314,780,784,885,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20833348$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lansdorp-Vogelaar, Iris, PhD</creatorcontrib><creatorcontrib>Knudsen, Amy B., PhD</creatorcontrib><creatorcontrib>Brenner, Hermann, MD, MPH</creatorcontrib><title>Cost-effectiveness of colorectal cancer screening – An overview</title><title>Baillière's best practice &amp; research. Clinical gastroenterology</title><addtitle>Best Pract Res Clin Gastroenterol</addtitle><description>There are several modalities available for a colorectal cancer (CRC) screening program. When determining which CRC screening program to implement, the costs of such programs should be considered in comparison to the health benefits they are expected to provide. Cost-effectiveness analysis provides a tool to do this. In this paper we review the evidence on the cost-effectiveness of CRC screening. Published studies universally indicate that when compared with no CRC screening, all screening modalities provide additional years of life at a cost that is deemed acceptable by most industrialized nations. Many recent studies even find CRC screening to be cost-saving. However, when the alternative CRC screening strategies are compared against each other in an incremental cost-effectiveness analysis, no single optimal strategy emerges across the studies. There is consensus that the new technologies of stool DNA testing, computed tomographic colonography and capsule endoscopy are not yet cost-effective compared with the established CRC screening tests.</description><subject>Capsule endoscopy</subject><subject>Capsule Endoscopy - economics</subject><subject>Colonography, Computed tomographic</subject><subject>Colonography, Computed Tomographic - economics</subject><subject>Colonoscopy</subject><subject>Colonoscopy - economics</subject><subject>Colorectal cancer</subject><subject>Colorectal neoplasms</subject><subject>Colorectal Neoplasms - diagnosis</subject><subject>Colorectal Neoplasms - economics</subject><subject>Colorectal Neoplasms - prevention &amp; control</subject><subject>Cost reduction</subject><subject>Cost-benefit analysis</subject><subject>Cost-Benefit Analysis - statistics &amp; numerical data</subject><subject>Cost-Benefit Analysis - trends</subject><subject>Deoxyribonucleic acid</subject><subject>DNA</subject><subject>Early Detection of Cancer - economics</subject><subject>Early Detection of Cancer - statistics &amp; numerical data</subject><subject>Early Detection of Cancer - trends</subject><subject>Feces</subject><subject>Female</subject><subject>Gastroenterology and Hepatology</subject><subject>Genetic testing</subject><subject>Humans</subject><subject>Intervention</subject><subject>Male</subject><subject>Mass screening</subject><subject>Mass Screening - economics</subject><subject>Mass Screening - methods</subject><subject>Mass Screening - trends</subject><subject>Mathematical models</subject><subject>Medical screening</subject><subject>Occult Blood</subject><subject>Quality standards</subject><subject>Quality-Adjusted Life Years</subject><subject>Sigmoidoscopy</subject><subject>Sigmoidoscopy - economics</subject><subject>Stool DNA</subject><subject>Studies</subject><issn>1521-6918</issn><issn>1532-1916</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9Ustu1DAUjRCIlsIHsEGRWLDKcP1KbCFVGo0oIFViAayvEudm8JCxBzszVXf8A3_YL8HRlAJdsPLrnCOfe05RPGewYMDq15tFt1svOOQzyAWAfFCcMiV4xQyrH857zqraMH1SPElpA5BJxjwuTjhoIYTUp8VyFdJU0TCQndyBPKVUhqG0YQwxX7VjaVtvKZbJRiLv_Lq8-fGzXPoyHCgeHF09LR4N7Zjo2e16Vny5ePt59b66_Pjuw2p5WVllzFR1piOtydpeSSW6ZuBSUSd5p6AlxcxQ93XNGmV415O2vK87YlJbpnpRN3oQZ8X5UXe377bUW_JTbEfcRbdt4zWG1uG_L959xXU4IDfCgDBZ4NWtQAzf95Qm3LpkaRxbT2GfsFESQDEFGfnyHnIT9tFnd8hA8EYarnlGsSPKxpBSpOHuLwxwzgc3mPPBOR8EiTmfzHnxt4k7xu9AMuDNEUB5lHm8EZN1lBPo3ZwH9sH9V_78HtuOzjvbjt_omtIfF5g4An6aCzL3g-VqgMqefgFDO7Zr</recordid><startdate>20100801</startdate><enddate>20100801</enddate><creator>Lansdorp-Vogelaar, Iris, PhD</creator><creator>Knudsen, Amy B., PhD</creator><creator>Brenner, Hermann, MD, MPH</creator><general>Elsevier Ltd</general><general>Elsevier Limited</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20100801</creationdate><title>Cost-effectiveness of colorectal cancer screening – An overview</title><author>Lansdorp-Vogelaar, Iris, PhD ; Knudsen, Amy B., PhD ; Brenner, Hermann, MD, MPH</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c599t-b9be88eccd5453b7f245eb42b50ae519f6d6617592bde8c2d6be148c15d3678f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Capsule endoscopy</topic><topic>Capsule Endoscopy - economics</topic><topic>Colonography, Computed tomographic</topic><topic>Colonography, Computed Tomographic - economics</topic><topic>Colonoscopy</topic><topic>Colonoscopy - economics</topic><topic>Colorectal cancer</topic><topic>Colorectal neoplasms</topic><topic>Colorectal Neoplasms - diagnosis</topic><topic>Colorectal Neoplasms - economics</topic><topic>Colorectal Neoplasms - prevention &amp; control</topic><topic>Cost reduction</topic><topic>Cost-benefit analysis</topic><topic>Cost-Benefit Analysis - statistics &amp; numerical data</topic><topic>Cost-Benefit Analysis - trends</topic><topic>Deoxyribonucleic acid</topic><topic>DNA</topic><topic>Early Detection of Cancer - economics</topic><topic>Early Detection of Cancer - statistics &amp; numerical data</topic><topic>Early Detection of Cancer - trends</topic><topic>Feces</topic><topic>Female</topic><topic>Gastroenterology and Hepatology</topic><topic>Genetic testing</topic><topic>Humans</topic><topic>Intervention</topic><topic>Male</topic><topic>Mass screening</topic><topic>Mass Screening - economics</topic><topic>Mass Screening - methods</topic><topic>Mass Screening - trends</topic><topic>Mathematical models</topic><topic>Medical screening</topic><topic>Occult Blood</topic><topic>Quality standards</topic><topic>Quality-Adjusted Life Years</topic><topic>Sigmoidoscopy</topic><topic>Sigmoidoscopy - economics</topic><topic>Stool DNA</topic><topic>Studies</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lansdorp-Vogelaar, Iris, PhD</creatorcontrib><creatorcontrib>Knudsen, Amy B., PhD</creatorcontrib><creatorcontrib>Brenner, Hermann, MD, MPH</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Baillière's best practice &amp; research. Clinical gastroenterology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lansdorp-Vogelaar, Iris, PhD</au><au>Knudsen, Amy B., PhD</au><au>Brenner, Hermann, MD, MPH</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cost-effectiveness of colorectal cancer screening – An overview</atitle><jtitle>Baillière's best practice &amp; research. Clinical gastroenterology</jtitle><addtitle>Best Pract Res Clin Gastroenterol</addtitle><date>2010-08-01</date><risdate>2010</risdate><volume>24</volume><issue>4</issue><spage>439</spage><epage>449</epage><pages>439-449</pages><issn>1521-6918</issn><eissn>1532-1916</eissn><coden>BPRCB6</coden><abstract>There are several modalities available for a colorectal cancer (CRC) screening program. When determining which CRC screening program to implement, the costs of such programs should be considered in comparison to the health benefits they are expected to provide. Cost-effectiveness analysis provides a tool to do this. In this paper we review the evidence on the cost-effectiveness of CRC screening. Published studies universally indicate that when compared with no CRC screening, all screening modalities provide additional years of life at a cost that is deemed acceptable by most industrialized nations. Many recent studies even find CRC screening to be cost-saving. However, when the alternative CRC screening strategies are compared against each other in an incremental cost-effectiveness analysis, no single optimal strategy emerges across the studies. There is consensus that the new technologies of stool DNA testing, computed tomographic colonography and capsule endoscopy are not yet cost-effective compared with the established CRC screening tests.</abstract><cop>Netherlands</cop><pub>Elsevier Ltd</pub><pmid>20833348</pmid><doi>10.1016/j.bpg.2010.04.004</doi><tpages>11</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 1521-6918
ispartof Baillière's best practice & research. Clinical gastroenterology, 2010-08, Vol.24 (4), p.439-449
issn 1521-6918
1532-1916
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2939039
source MEDLINE; ScienceDirect Journals (5 years ago - present)
subjects Capsule endoscopy
Capsule Endoscopy - economics
Colonography, Computed tomographic
Colonography, Computed Tomographic - economics
Colonoscopy
Colonoscopy - economics
Colorectal cancer
Colorectal neoplasms
Colorectal Neoplasms - diagnosis
Colorectal Neoplasms - economics
Colorectal Neoplasms - prevention & control
Cost reduction
Cost-benefit analysis
Cost-Benefit Analysis - statistics & numerical data
Cost-Benefit Analysis - trends
Deoxyribonucleic acid
DNA
Early Detection of Cancer - economics
Early Detection of Cancer - statistics & numerical data
Early Detection of Cancer - trends
Feces
Female
Gastroenterology and Hepatology
Genetic testing
Humans
Intervention
Male
Mass screening
Mass Screening - economics
Mass Screening - methods
Mass Screening - trends
Mathematical models
Medical screening
Occult Blood
Quality standards
Quality-Adjusted Life Years
Sigmoidoscopy
Sigmoidoscopy - economics
Stool DNA
Studies
title Cost-effectiveness of colorectal cancer screening – An overview
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-06T22%3A52%3A37IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Cost-effectiveness%20of%20colorectal%20cancer%20screening%20%E2%80%93%20An%20overview&rft.jtitle=Bailli%C3%A8re's%20best%20practice%20&%20research.%20Clinical%20gastroenterology&rft.au=Lansdorp-Vogelaar,%20Iris,%20PhD&rft.date=2010-08-01&rft.volume=24&rft.issue=4&rft.spage=439&rft.epage=449&rft.pages=439-449&rft.issn=1521-6918&rft.eissn=1532-1916&rft.coden=BPRCB6&rft_id=info:doi/10.1016/j.bpg.2010.04.004&rft_dat=%3Cproquest_pubme%3E754005150%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1032749282&rft_id=info:pmid/20833348&rft_els_id=1_s2_0_S1521691810000582&rfr_iscdi=true