Proteomics Identification of Drosophila Small Interfering RNA-associated Factors

The Drosophila melanogaster RNA-induced silencing complex (RISC) forms a large ribonucleoprotein particle on small interfering RNAs (siRNAs) and catalyzes target mRNA cleavage during RNA interference (RNAi). Dicer-2, R2D2, Loquacious, and Argonaute-2 are examples of RISC-associated factors that are...

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Veröffentlicht in:	Molecular & cellular proteomics 2010-09, Vol.9 (9), p.1866-1872
Hauptverfasser:	Gerbasi, Vincent R., Golden, Daniel E., Hurtado, Sara B., Sontheimer, Erik J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence Cells, Cultured Chromatography, Affinity Cluster Analysis Drosophila melanogaster Drosophila Proteins - metabolism Proteomics RNA, Small Interfering - metabolism Spectrometry, Mass, Electrospray Ionization Tandem Mass Spectrometry
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