TGFβ/BMP Type I Receptors ALK1 and ALK2 Are Essential for BMP9-induced Osteogenic Signaling in Mesenchymal Stem Cells[S]

Mesenchymal stem cells (MSCs) are bone marrow stromal cells that can differentiate into multiple lineages. We previously demonstrated that BMP9 is one of the most potent BMPs to induce osteogenic differentiation of MSCs. BMP9 is one of the least studied BMPs. Whereas ALK1, ALK5, and/or endoglin have...

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Veröffentlicht in:	The Journal of biological chemistry 2010-09, Vol.285 (38), p.29588-29598
Hauptverfasser:	Luo, Jinyong, Tang, Min, Huang, Jiayi, He, Bai-Cheng, Gao, Jian-Li, Chen, Liang, Zuo, Guo-Wei, Zhang, Wenli, Luo, Qing, Shi, Qiong, Zhang, Bing-Qiang, Bi, Yang, Luo, Xiaoji, Jiang, Wei, Su, Yuxi, Shen, Jikun, Kim, Stephanie H., Huang, Enyi, Gao, Yanhong, Zhou, Jian-Zhong, Yang, Ke, Luu, Hue H., Pan, Xiaochuan, Haydon, Rex C., Deng, Zhong-Liang, He, Tong-Chuan
Format:	Artikel
Sprache:	eng
Schlagworte:	ALk Receptors BMP-9 Bone Bone Morphogenetic Protein (BMP) Cell Biology Cell Differentiation Mesenchymal Stem Cells Osteogenic Differentiation Protein-Protein Interactions Signal Transduction TGFb Type I Receptors
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