α-Synuclein gene duplication impairs reward learning

α-Synuclein (SNCA) plays an important role in the regulation of dopaminergic neurotransmission and neurodegeneration in Parkinson disease. We investigated reward and punishment learning in asymptomatic carriers of a rare SNCA gene duplication who were healthy siblings of patients with Parkinson dise...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2010-09, Vol.107 (36), p.15992-15994
Hauptverfasser:	Kéri, Szabolcs, Moustafa, Ahmed A, Myers, Catherine E, Benedek, György, Gluck, Mark A
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological Sciences Drug carriers Educational administration Experimentation Gene duplication Grants Learning Neurons Parkinson disease Parkinsonian disorders Symptoms
Online-Zugang:	Volltext
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