Mycobacterium tuberculosis Dihydrofolate Reductase Is Not a Target Relevant to the Antitubercular Activity of Isoniazid
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| Veröffentlicht in: | Antimicrobial Agents and Chemotherapy 2010-09, Vol.54 (9), p.3776-3782 |
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| creator | Wang, Feng Jain, Paras Gulten, Gulcin Liu, Zhen Feng, Yicheng Ganesula, Krishna Motiwala, Alifiya S Ioerger, Thomas R Alland, David Vilchèze, Catherine Jacobs, Jr, William R Sacchettini, James C |
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| doi_str_mv | 10.1128/AAC.00453-10 |
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Print ISSN:
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</description><identifier>ISSN: 0066-4804</identifier><identifier>EISSN: 1098-6596</identifier><identifier>DOI: 10.1128/AAC.00453-10</identifier><identifier>PMID: 20566771</identifier><language>eng</language><publisher>United States: American Society for Microbiology</publisher><subject>Antitubercular Agents ; Antitubercular Agents - pharmacology ; Escherichia coli ; Isoniazid ; Isoniazid - pharmacology ; Mechanisms of Action: Physiological Effects ; Microbial Sensitivity Tests ; Mutation ; Mycobacterium tuberculosis ; Mycobacterium tuberculosis - drug effects ; Mycobacterium tuberculosis - enzymology ; Mycobacterium tuberculosis - genetics ; Tetrahydrofolate Dehydrogenase ; Tetrahydrofolate Dehydrogenase - genetics ; Tetrahydrofolate Dehydrogenase - physiology ; Transformation, Genetic - genetics</subject><ispartof>Antimicrobial Agents and Chemotherapy, 2010-09, Vol.54 (9), p.3776-3782</ispartof><rights>Copyright © 2010 American Society for Microbiology</rights><rights>Copyright © 2010, American Society for Microbiology 2010</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a475t-6edd90b013a8397ff2b08e1075e9467a3e4a31bf89e1c9e0c86a8419cf9991a33</citedby><cites>FETCH-LOGICAL-a475t-6edd90b013a8397ff2b08e1075e9467a3e4a31bf89e1c9e0c86a8419cf9991a33</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2935018/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2935018/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27903,27904,53769,53771</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20566771$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wang, Feng</creatorcontrib><creatorcontrib>Jain, Paras</creatorcontrib><creatorcontrib>Gulten, Gulcin</creatorcontrib><creatorcontrib>Liu, Zhen</creatorcontrib><creatorcontrib>Feng, Yicheng</creatorcontrib><creatorcontrib>Ganesula, Krishna</creatorcontrib><creatorcontrib>Motiwala, Alifiya S</creatorcontrib><creatorcontrib>Ioerger, Thomas R</creatorcontrib><creatorcontrib>Alland, David</creatorcontrib><creatorcontrib>Vilchèze, Catherine</creatorcontrib><creatorcontrib>Jacobs, Jr, William R</creatorcontrib><creatorcontrib>Sacchettini, James C</creatorcontrib><title>Mycobacterium tuberculosis Dihydrofolate Reductase Is Not a Target Relevant to the Antitubercular Activity of Isoniazid</title><title>Antimicrobial Agents and Chemotherapy</title><addtitle>AAC</addtitle><addtitle>Antimicrob Agents Chemother</addtitle><description>Classifications
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</description><subject>Antitubercular Agents</subject><subject>Antitubercular Agents - pharmacology</subject><subject>Escherichia coli</subject><subject>Isoniazid</subject><subject>Isoniazid - pharmacology</subject><subject>Mechanisms of Action: Physiological Effects</subject><subject>Microbial Sensitivity Tests</subject><subject>Mutation</subject><subject>Mycobacterium tuberculosis</subject><subject>Mycobacterium tuberculosis - drug effects</subject><subject>Mycobacterium tuberculosis - enzymology</subject><subject>Mycobacterium tuberculosis - genetics</subject><subject>Tetrahydrofolate Dehydrogenase</subject><subject>Tetrahydrofolate Dehydrogenase - genetics</subject><subject>Tetrahydrofolate Dehydrogenase - physiology</subject><subject>Transformation, Genetic - genetics</subject><issn>0066-4804</issn><issn>1098-6596</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkU1v1DAQhi0EokvhxhmZE0IixY4dJ74gRctXpQISKmdr4kw2rrJxaztbLb8el20rOCBOlj2PH83MS8hzzk44L5u3bbs-YUxWouDsAVlxpptCVVo9JCvGlCpkw-QReRLjBcv3SrPH5KhklVJ1zVfk-sve-g5swuCWLU1Lh8Euk48u0vdu3PfBD36ChPQ79otNEJGeRvrVJwr0HMIGU65MuIM50eRpGpG2c3J3Igi0tcntXNpTP-Svfnbw0_VPyaMBpojPbs9j8uPjh_P15-Ls26fTdXtWgKyrVCjse806xgU0QtfDUHasQc7qCrVUNQiUIHg3NBq51chso6CRXNtBa81BiGPy7uC9XLot9hbnFGAyl8FtIeyNB2f-rsxuNBu_M6UWFeNNFry6FQR_tWBMZuuixWmCGf0STV3JRldSq_-TGVRcyxvnmwNpg48x4HDfD2fmJlSTQzW_Q80vGX99wCFuS3PhlzDnlf2LffHnvPfiu8Qz8PIAjG4zXruAJlsNgDWVNNqIulbiF7yatu0</recordid><startdate>20100901</startdate><enddate>20100901</enddate><creator>Wang, Feng</creator><creator>Jain, Paras</creator><creator>Gulten, Gulcin</creator><creator>Liu, Zhen</creator><creator>Feng, Yicheng</creator><creator>Ganesula, Krishna</creator><creator>Motiwala, Alifiya S</creator><creator>Ioerger, Thomas R</creator><creator>Alland, David</creator><creator>Vilchèze, Catherine</creator><creator>Jacobs, Jr, William R</creator><creator>Sacchettini, James C</creator><general>American Society for Microbiology</general><general>American Society for Microbiology (ASM)</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7QL</scope><scope>7T7</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>P64</scope><scope>5PM</scope></search><sort><creationdate>20100901</creationdate><title>Mycobacterium tuberculosis Dihydrofolate Reductase Is Not a Target Relevant to the Antitubercular Activity of Isoniazid</title><author>Wang, Feng ; 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</abstract><cop>United States</cop><pub>American Society for Microbiology</pub><pmid>20566771</pmid><doi>10.1128/AAC.00453-10</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0066-4804 |
| ispartof | Antimicrobial Agents and Chemotherapy, 2010-09, Vol.54 (9), p.3776-3782 |
| issn | 0066-4804 1098-6596 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2935018 |
| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
| subjects | Antitubercular Agents Antitubercular Agents - pharmacology Escherichia coli Isoniazid Isoniazid - pharmacology Mechanisms of Action: Physiological Effects Microbial Sensitivity Tests Mutation Mycobacterium tuberculosis Mycobacterium tuberculosis - drug effects Mycobacterium tuberculosis - enzymology Mycobacterium tuberculosis - genetics Tetrahydrofolate Dehydrogenase Tetrahydrofolate Dehydrogenase - genetics Tetrahydrofolate Dehydrogenase - physiology Transformation, Genetic - genetics |
| title | Mycobacterium tuberculosis Dihydrofolate Reductase Is Not a Target Relevant to the Antitubercular Activity of Isoniazid |
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