A capillary electrophoresis method for evaluation of Aβ proteolysis in vitro

According to the amyloid hypothesis, Aβ peptides are neurotoxic and underlie development and progression of Alzheimer’s disease (AD). Multiple Aβ clearance mechanisms, including destruction of the peptides by proteolytic enzymes, are hypothesized to regulate physiological Aβ peptide levels. The insu...

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Veröffentlicht in:	Journal of neuroscience methods 2009-03, Vol.178 (1), p.40-45
Hauptverfasser:	Alper, Benjamin J., Schmidt, Walter K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer's disease Amyloid beta Capillary electrophoresis Insulin-degrading enzyme
Online-Zugang:	Volltext
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