Discovery of a Pro-neurogenic, Neuroprotective Chemical

An in vivo screen was performed in search of chemicals capable of enhancing neuron formation in the hippocampus of adult mice. Eight of 1,000 small molecules tested enhanced neuron formation in the subgranular zone of the dentate gyrus. Among these was an aminopropyl carbazole, designated P7C3, endo...

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Veröffentlicht in:	Cell 2010-07, Vol.142 (1), p.39-51
Hauptverfasser:	Pieper, Andrew A., Xie, Shanhai, Capota, Ema, Estill, Sandi Jo, Zhong, Jeannie, Long, Jeffrey M., Becker, Ginger L., Huntington, Paula, Goldman, Shauna E., Shen, Ching-Han, Capota, Maria, Britt, Jeremiah K., Kotti, Tiina, Ure, Kerstin, Brat, Daniel J., Williams, Noelle S., MacMillan, Karen S., Naidoo, Jacinth, Melito, Lisa, Hsieh, Jenny, De Brabander, Jef, Ready, Joseph M., McKnight, Steven L.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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