Intraneuronal angiotensinergic system in rat and human dorsal root ganglia

To elucidate the local formation of angiotensin II (Ang II) in the neurons of sensory dorsal root ganglia (DRG), we studied the expression of angiotensinogen (Ang-N)-, renin-, angiotensin converting enzyme (ACE)- and cathepsin D-mRNA, and the presence of protein renin, Ang II, Substance P and calcit...

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Veröffentlicht in:	Regulatory peptides 2010-06, Vol.162 (1), p.90-98
Hauptverfasser:	Patil, Jaspal, Schwab, Alexander, Nussberger, Juerg, Schaffner, Thomas, Saavedra, Juan M., Imboden, Hans
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin II Angiotensinogen - genetics Angiotensins - metabolism Animals Base Sequence Biological and medical sciences Cathepsin D - genetics Chromatography, High Pressure Liquid DNA Primers Fundamental and applied biological sciences. Psychology Ganglia, Spinal - metabolism Humans Immunohistochemistry Male Neuronal angiotensin Neurons - metabolism Neurotransmitter Peptidyl-Dipeptidase A - genetics Rats Rats, Inbred WKY Renin–angiotensin system Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - genetics Sensory system Vertebrates: endocrinology
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