Dynamic patterning at the pylorus: Formation of an epithelial intestine–stomach boundary in late fetal life

In the adult mouse, distinct morphological and transcriptional differences separate stomach from intestinal epithelium. Remarkably, the epithelial boundary between these two organs is literally one cell thick. This discrete junction is established suddenly and precisely at embryonic day (E) 16.5, by...

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Veröffentlicht in:	Developmental dynamics 2009-12, Vol.238 (12), p.3205-3217
Hauptverfasser:	Li, Xing, Udager, Aaron M., Hu, Chunbo, Qiao, Xiaotan T., Richards, Neil, Gumucio, Deborah L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Embryo, Mammalian Female Fetal Development - genetics Fetal Development - physiology Gata3 Gene Expression Profiling Gestational Age Hedgehog signaling intestinal identity Intestinal Mucosa - embryology Intestinal Mucosa - metabolism Intestines - embryology Intestines - metabolism Kruppel-Like Transcription Factors - genetics Lac Operon - genetics Mice Mice, Inbred C57BL Mice, Transgenic microarray analysis Oligonucleotide Array Sequence Analysis Pregnancy Pylorus - embryology Pylorus - metabolism Stomach - embryology Stomach - metabolism Wnt signaling Zinc Finger Protein GLI1
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