Moesin1 and Ve-cadherin are required in endothelial cells during in vivo tubulogenesis

Endothelial tubulogenesis is a crucial step in the formation of functional blood vessels during angiogenesis and vasculogenesis. Here, we use in vivo imaging of living zebrafish embryos expressing fluorescent fusion proteins of beta-Actin, alpha-Catenin, and the ERM family member Moesin1 (Moesin a),...

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Veröffentlicht in:	Development (Cambridge) 2010-09, Vol.137 (18), p.3119-3128
Hauptverfasser:	Wang, Ying, Kaiser, Mark S, Larson, Jon D, Nasevicius, Aidas, Clark, Karl J, Wadman, Shannon A, Roberg-Perez, Sharon E, Ekker, Stephen C, Hackett, Perry B, McGrail, Maura, Essner, Jeffrey J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adherens Junctions - metabolism Animals Antigens, CD - genetics Antigens, CD - metabolism Cadherins - genetics Cadherins - metabolism Cell Polarity Danio rerio Embryo, Nonmammalian - blood supply Embryo, Nonmammalian - metabolism Endothelial Cells - cytology Endothelial Cells - metabolism Freshwater Gene Expression Regulation, Developmental Membrane Proteins - genetics Membrane Proteins - metabolism Microfilament Proteins - deficiency Microfilament Proteins - genetics Microfilament Proteins - metabolism Neovascularization, Physiologic Phosphoproteins - genetics Phosphoproteins - metabolism Zebrafish - embryology Zebrafish - genetics Zebrafish - metabolism Zonula Occludens-1 Protein
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