Bothrops snake myotoxins induce a large efflux of ATP and potassium with spreading of cell damage and pain

Myotoxins play a major role in the pathogenesis of the envenomations caused by snake bites in large parts of the world where this is a very relevant public health problem. We show here that two myotoxins that are major constituents of the venom of Bothrops asper, a deadly snake present in Latin Amer...

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Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 2010-08, Vol.107 (32), p.14140-14145
Hauptverfasser: Cintra-Francischinelli, Mariana, Caccin, Paola, Chiavegato, Angela, Pizzo, Paola, Carmignoto, Giorgio, Angulo, Yamileth, Lomonte, Bruno, Gutiérrez, José María, Montecucco, Cesare, Rappuoli, Rino
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Sprache:eng
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