WASP family proteins: their evolution and its physiological implications

WASP family proteins control actin polymerization by activating the Arp2/3 complex. Several subfamilies exist, but their regulation and physiological roles are not well understood, nor is it even known if all subfamilies have been identified. Our extensive search reveals few novel WASP family protei...

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Veröffentlicht in:	Molecular biology of the cell 2010-08, Vol.21 (16), p.2880-2893
Hauptverfasser:	Veltman, Douwe M, Insall, Robert H
Format:	Artikel
Sprache:	eng
Schlagworte:	Actin-Related Protein 2-3 Complex - genetics Actin-Related Protein 2-3 Complex - metabolism Amino Acid Motifs Amino Acid Sequence Animals Binding Sites - genetics Conserved Sequence Dictyostelium Dictyostelium - cytology Dictyostelium - genetics Dictyostelium - metabolism Evolution, Molecular Green Fluorescent Proteins - classification Green Fluorescent Proteins - genetics Green Fluorescent Proteins - physiology Humans Hymenoptera Microscopy, Fluorescence - methods Molecular Sequence Data Phylogeny Protozoan Proteins - genetics Protozoan Proteins - metabolism Protozoan Proteins - physiology Sequence Homology, Amino Acid Wiskott-Aldrich Syndrome Protein - classification Wiskott-Aldrich Syndrome Protein - genetics Wiskott-Aldrich Syndrome Protein - metabolism Wiskott-Aldrich Syndrome Protein Family - classification Wiskott-Aldrich Syndrome Protein Family - genetics Wiskott-Aldrich Syndrome Protein Family - metabolism
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