Regulation of interleukin-1β by interferon-γ is species specific, limited by suppressor of cytokine signalling 1 and influences interleukin-17 production

Reports describing the effect of interferon‐γ (IFNγ) on interleukin‐1β (IL‐1β) production are conflicting. We resolve this controversy by showing that IFNγ potentiates IL‐1β release from human cells, but transiently inhibits the production of IL‐1β from mouse cells. Release from this inhibition is d...

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Veröffentlicht in:	EMBO reports 2010-08, Vol.11 (8), p.640-646
Hauptverfasser:	Masters, Seth L, Mielke, Lisa A, Cornish, Ann L, Sutton, Caroline E, O'Donnell, Joanne, Cengia, Louise H, Roberts, Andrew W, Wicks, Ian P, Mills, Kingston H G, Croker, Ben A
Format:	Artikel
Sprache:	eng
Schlagworte:	EMBO19 EMBO24 EMBO37 IFNγ IL-17 IL-1β inflammasome Scientific Report Scientific Reports SOCS1
Online-Zugang:	Volltext
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