Relative risk estimated from the ratio of two median unbiased estimates

Clinical trials often include binary end points. In some cases, no successes are observed and the usual large sample estimates of relative risk are undefined. The paper proposes an estimator for relative risk based on the median unbiased estimator. The relative risk estimator proposed is well define...

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Veröffentlicht in:Applied statistics 2010-08, Vol.59 (4), p.657-671
Hauptverfasser: Carter, Rickey E., Lin, Yan, Lipsitz, Stuart R., Newcombe, Robert G., Hermayer, Kathie L.
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Sprache:eng
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