RNA‐binding protein Csx1 mediates global control of gene expression in response to oxidative stress

Fission yeast Spc1 (Sty1), a stress‐activated mitogen‐activated protein kinase (MAPK) homologous to human p38, orchestrates global changes in gene expression in response to diverse forms of cytotoxic stress. This control is partly mediated through Atf1, a transcription factor homologous to human ATF...

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Veröffentlicht in:	The EMBO journal 2003-12, Vol.22 (23), p.6256-6266
Hauptverfasser:	Rodríguez‐Gabriel, Miguel A., Burns, Gavin, McDonald, W. Hayes, Martín, Victoria, Yates, John R., Bähler, Jürg, Russell, Paul
Format:	Artikel
Sprache:	eng
Schlagworte:	Atf1 protein Csx1 protein EMBO36 EMBO37 Fungal Proteins - genetics Gene Expression Regulation - physiology Homeobox Protein Nkx-2.5 Homeodomain Proteins - chemistry Homeodomain Proteins - metabolism microarray Mutagenesis, Insertional Oligonucleotide Array Sequence Analysis Oxidative stress Oxidative Stress - physiology Phosphorylation post‐transcriptional control of gene expression Recombinant Proteins - chemistry Recombinant Proteins - metabolism RNA, Messenger - genetics RNA-Binding Proteins - chemistry RNA-Binding Proteins - metabolism RNA‐binding protein Schizosaccharomyces - genetics Schizosaccharomyces pombe Transcription Factors - chemistry Transcription Factors - metabolism Yeasts
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