Mucin gene 19 (MUC19) expression and response to inflammatory cytokines in middle ear epithelium

Mucin gene 19 (MUC19) has been identified as a major gel-forming mucin in the human middle ear (ME). The objectives of this investigation were to characterize the expression and assess the regulation of MUC19 in the ME cell culture models utilized in the study of otitis media (OM). Findings demonstr...

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Veröffentlicht in:	Glycoconjugate journal 2009-12, Vol.26 (9), p.1275-1284
Hauptverfasser:	Kerschner, Joseph E, Khampang, Pawjai, Erbe, Christy B, Kolker, Alexander, Cioffi, Joseph A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biochemistry Biomedical and Life Sciences Cell culture Chinchilla Cytokines - pharmacology Ear diseases Ear, Middle - metabolism Epithelial Cells - cytology Epithelial Cells - drug effects Epithelial Cells - metabolism Epithelium - drug effects Epithelium - metabolism Gene expression Gene Expression Regulation - drug effects Humans Inflammation Mediators - pharmacology Inflammatory diseases Interleukin-1beta - pharmacology Interleukin-6 - pharmacology Interleukin-8 - pharmacology Life Sciences Mucins - genetics Mucins - metabolism Pathology Polymerase Chain Reaction Rodentia Time Factors Tumor Necrosis Factor-alpha - pharmacology
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