Microdeletions of 3q29 Confer High Risk for Schizophrenia

Schizophrenia (SZ) is a severe psychiatric illness that affects ∼1% of the population and has a strong genetic underpinning. Recently, genome-wide analysis of copy-number variation (CNV) has implicated rare and de novo events as important in SZ. Here, we report a genome-wide analysis of 245 SZ cases...

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Veröffentlicht in:	American journal of human genetics 2010-08, Vol.87 (2), p.229-236
Hauptverfasser:	Mulle, Jennifer Gladys, Dodd, Anne F., McGrath, John A., Wolyniec, Paula S., Mitchell, Adele A., Shetty, Amol C., Sobreira, Nara L., Valle, David, Rudd, M. Katharine, Satten, Glen, Cutler, David J., Pulver, Ann E., Warren, Stephen T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult and adolescent clinical studies Base Pairing - genetics Biological and medical sciences Case-Control Studies Chromosomes, Human, Pair 3 - genetics Classical genetics, quantitative genetics, hybrids DNA Copy Number Variations - genetics Fundamental and applied biological sciences. Psychology General aspects. Genetic counseling Genes Genetic Loci - genetics Genetic Predisposition to Disease Genetics of eukaryotes. Biological and molecular evolution Genomics Human Humans Medical genetics Medical sciences Molecular and cellular biology Physical Chromosome Mapping Psychiatry Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Psychoses Reproducibility of Results Risk assessment Schizophrenia Schizophrenia - genetics Sequence Deletion - genetics Young Adult
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