Differential neuronal vulnerability varies according to specific cardiopulmonary bypass insult in a porcine survival model

Objective We investigated whether the degree of vulnerability of different areas in the developing brain varies according to the specific mechanism of the insults caused by cardiopulmonary bypass. Methods A meta-analysis of 2 experimental studies (n = 80) was conducted. The end points of the otherwi...

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Veröffentlicht in:	The Journal of thoracic and cardiovascular surgery 2010-12, Vol.140 (6), p.1408-1415.e3
Hauptverfasser:	Ishibashi, Nobuyuki, MD, Iwata, Yusuke, MD, Okamura, Toru, MD, Zurakowski, David, PhD, Lidov, Hart G.W., MD, Jonas, Richard A., MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Animals Aprotinin - pharmacology Biological and medical sciences Brain Ischemia - etiology Brain Ischemia - pathology Cardiology. Vascular system Cardiopulmonary Bypass Cardiothoracic Surgery Caudate Nucleus - pathology Data Interpretation, Statistical Disease Models, Animal Inflammation - pathology Medical sciences Microcirculation Neurons - pathology Oxygen - metabolism Pneumology Swine Vasoconstriction
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