Estrogen-dependent Transcription of the NEL-like 2 (NELL2) Gene and Its Role in Protection from Cell Death

NELL2 (neural tissue-specific epidermal growth factor-like repeat domain-containing protein) is a secreted glycoprotein that is predominantly expressed in neural tissues. We reported previously that NELL2 mRNA abundance in brain is increased by estrogen (E2) treatment and that NELL2 is involved in t...

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Veröffentlicht in:	The Journal of biological chemistry 2010-08, Vol.285 (32), p.25074-25084
Hauptverfasser:	Choi, Eun Jung, Kim, Dong Hee, Kim, Jae Geun, Kim, Dong Yeol, Kim, Jung Dae, Seol, Ok Ju, Jeong, Choon Soo, Park, Jeong Woo, Choi, Min Young, Kang, Sung Goo, Costa, Maria E., Ojeda, Sergio R., Lee, Byung Ju
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Cell Death DNA Primers - genetics Estrogen Estrogens - metabolism Gene Expression Gene Expression Regulation Gene Regulation Half-ERE Hippocampus - metabolism Mice Mitogen-Activated Protein Kinase 3 - metabolism Models, Biological NELL2 Nerve Tissue Proteins - metabolism Neurobiology Neuroprogenitor Cell Promoter Regions, Genetic Protein Structure, Tertiary Response Elements Signal Transduction Transcription Regulation
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