Is Nostoc H-NOX a NO Sensor or Redox Switch?

Nostoc sp. (Ns) H-NOX is a heme protein found in symbiotic cyanobacteria, which has ∼35% sequence identity and high structural homology to the β subunit of soluble guanylyl cyclase (sGC), suggesting a NO sensing function. However, UV−vis, EPR, NIR MCD, and ligand binding experiments with ferrous and...

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Veröffentlicht in:	Biochemistry (Easton) 2010-08, Vol.49 (31), p.6587-6599
Hauptverfasser:	Tsai, Ah-Lim, Berka, Vladimir, Martin, Faye, Ma, Xiaolei, van den Akker, Focco, Fabian, Marian, Olson, John S
Format:	Artikel
Sprache:	eng
Schlagworte:	Cyanobacteria Guanylate Cyclase - metabolism Guanylate Cyclase - physiology NADH, NADPH Oxidoreductases - metabolism NADH, NADPH Oxidoreductases - physiology Nitric Oxide - metabolism Nostoc - enzymology Nostoc - metabolism Oxidation-Reduction Protein Binding Protein Conformation Receptors, Cytoplasmic and Nuclear - metabolism Receptors, Cytoplasmic and Nuclear - physiology Sequence Homology, Amino Acid Soluble Guanylyl Cyclase Spectrum Analysis Structural Homology, Protein
Online-Zugang:	Volltext
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