Thioglycoligase-Based Assembly of Thiodisaccharides: Screening as β-Galactosidase Inhibitors

New way of doing things. An efficient inhibitor of a human lysosomal acid β‐galactosidase was identified through screening of a small collection of thioglycosides created by using a thioglycoligase derived from a bacterial β‐galactosidase (see scheme). The results described here open the interesting...

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Veröffentlicht in:Chembiochem : a European journal of chemical biology 2007-09, Vol.8 (13), p.1495-1499
Hauptverfasser: Kim, Young-Wan, Chen, Hong-Ming, Kim, Jin Hyo, Müllegger, Johannes, Mahuran, Don, Withers, Stephen G
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Sprache:eng
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