Glutathione depletion enhances arsenic trioxide‐induced apoptosis in lymphoma cells through mitochondrial‐independent mechanisms

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Veröffentlicht in:British journal of haematology 2010-08, Vol.150 (3), p.365-369
Hauptverfasser: Bhalla, Savita, Gordon, Leo I., David, Kevin, Prachand, Sheila, Singh, Amareshwar T.K., Yang, Shuo, Winter, Jane N., Guo, Dongsheng, O’Halloran, Thomas, Platanias, Leonidas C., Evens, Andrew M.
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container_title British journal of haematology
container_volume 150
creator Bhalla, Savita
Gordon, Leo I.
David, Kevin
Prachand, Sheila
Singh, Amareshwar T.K.
Yang, Shuo
Winter, Jane N.
Guo, Dongsheng
O’Halloran, Thomas
Platanias, Leonidas C.
Evens, Andrew M.
description
doi_str_mv 10.1111/j.1365-2141.2010.08197.x
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subjects Antineoplastic Agents - pharmacology
apoptosis
Apoptosis - drug effects
arsenic trioxide
Arsenicals - pharmacology
Biological and medical sciences
Glutathione - physiology
Hematologic and hematopoietic diseases
Humans
Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
Lymphoma - pathology
Medical sciences
Mitochondria - physiology
non‐Hodgkin lymphoma
oxidative stress
Oxides - pharmacology
reactive oxygen species
title Glutathione depletion enhances arsenic trioxide‐induced apoptosis in lymphoma cells through mitochondrial‐independent mechanisms
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