ERM is required for transcriptional control of the spermatogonial stem cell niche

Division of spermatogonial stem cells produces daughter cells that either maintain their stem cell identity or undergo differentiation to form mature sperm. The Sertoli cell, the only somatic cell within seminiferous tubules, provides the stem cell niche through physical support and expression of su...

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Veröffentlicht in:	Nature 2005-08, Vol.436 (7053), p.1030-1034
Hauptverfasser:	Chen, Chen, Chandrashekar, Varadaraj, Arber, Silvia, Carnes, Kay, Cheng, Alec M, Murphy, Theresa L, Grigura, Vadim, Lim, Hyunjung, Hofmann, Marie-Claude, Ouyang, Wenjun, Zhou, Qing, Hess, Rex A, Murphy, Kenneth M, Zhao, Guang-Quan, Hassell, John A, Kurpios, Natasza
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Biological and medical sciences Cell division Cell Proliferation DNA-Binding Proteins - deficiency DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism Fundamental and applied biological sciences. Psychology Gene Deletion Gene Expression Profiling Hormone metabolism and regulation Humanities and Social Sciences letter Male Mammalian male genital system Mice Mice, Knockout multidisciplinary Oligonucleotide Array Sequence Analysis Reproductive system Science Science (multidisciplinary) Sertoli Cells - cytology Sertoli Cells - metabolism Spermatogenesis - genetics Spermatogonia - cytology Stem cells Stem Cells - cytology Stem Cells - metabolism Tissues Transcription Factors - deficiency Transcription Factors - genetics Transcription Factors - metabolism Transcription, Genetic Vertebrates: reproduction
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