Regulation of homocysteine metabolism and methylation in human and mouse tissues

Hyperhomocysteinemia is an independent risk factor for cardiovascular disease. Homocysteine (Hcy) metabolism involves multiple enzymes; however, tissue Hcy metabolism and its relevance to methylation remain unknown. Here, we established gene expression profiles of 8 Hcy metabolic and 12 methylation...

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Veröffentlicht in:The FASEB journal 2010-08, Vol.24 (8), p.2804-2817
Hauptverfasser: Chen, Natalie C, Yang, Fan, Capecci, Louis M, Gu, Ziyu, Schafer, Andrew I, Durante, William, Yang, Xiao-Feng, Wang, Hong
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Sprache:eng
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