Toll-like Receptor 3 Regulates Angiogenesis and Apoptosis in Prostate Cancer Cell Lines through Hypoxia-Inducible Factor 1α1

Toll-like receptors (TLRs) recognize microbial/viral-derived components that trigger innate immune response and conflicting data implicate TLR agonists in cancer, either as protumor or antitumor agents. We previously demonstrated that TLR3 activation mediated by its agonist poly(I:C) induces antitum...

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Veröffentlicht in:Neoplasia (New York, N.Y.) N.Y.), 2010-07, Vol.12 (7), p.539-549
Hauptverfasser: Paone, Alessio, Galli, Roberta, Gabellini, Chiara, Lukashev, Dmitriy, Starace, Donatella, Gorlach, Agnes, De Cesaris, Paola, Ziparo, Elio, Del Bufalo, Donatella, Sitkovsky, Michail V, Filippini, Antonio, Riccioli, Anna
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Sprache:eng
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