Developmental Switch in the Contribution of Presynaptic and Postsynaptic NMDA Receptors to Long-Term Depression

NMDA receptor (NMDAR) activation is required for many forms of learning and memory as well as sensory system receptive field plasticity, yet the relative contribution of presynaptic and postsynaptic NMDARs over cortical development remains unknown. Here we demonstrate a rapid developmental loss of f...

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Veröffentlicht in:	The Journal of neuroscience 2007-09, Vol.27 (37), p.9835-9845
Hauptverfasser:	Corlew, Rebekah, Wang, Yun, Ghermazien, Haben, Erisir, Alev, Philpot, Benjamin D
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Newborn Excitatory Postsynaptic Potentials - physiology Gene Expression Regulation, Developmental Genes, Switch - physiology Long-Term Synaptic Depression - physiology Mice Mice, Inbred C57BL Neocortex - growth & development Receptors, N-Methyl-D-Aspartate - physiology Receptors, Presynaptic - physiology
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