Isolation of male germ-line stem cells; influence of GDNF

The identification and physical isolation of testis stem cells, a subset of type A spermatogonia, is critical to our understanding of their growth regulation during the first steps of spermatogenesis. These stem cells remain poorly characterized because of the paucity of specific molecular markers t...

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Veröffentlicht in:	Developmental biology 2005-03, Vol.279 (1), p.114-124
Hauptverfasser:	Hofmann, Marie-Claude, Braydich-Stolle, Laura, Dym, Martin
Format:	Artikel
Sprache:	eng
Schlagworte:	Affymetrix microarray Animals Cell Cycle Cell Differentiation Cell Division Cell Separation FGF2 GDNF GFRα-1 Glial Cell Line-Derived Neurotrophic Factor Glial Cell Line-Derived Neurotrophic Factor Receptors Male Mice Nerve Growth Factors - genetics Nerve Growth Factors - physiology Proto-Oncogene Proteins - genetics Proto-Oncogene Proteins - physiology Proto-Oncogene Proteins c-ret Receptor Protein-Tyrosine Kinases - genetics Receptor Protein-Tyrosine Kinases - physiology Reverse Transcriptase Polymerase Chain Reaction Spermatogonia - cytology Spermatogonia - drug effects Spermatogonia - physiology Stem cell Testis - physiology Type A spermatogonia
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