Improved outcome with pulses of vincristine and corticosteroids in continuation therapy of children with average risk acute lymphoblastic leukemia (ALL) and lymphoblastic non-Hodgkin lymphoma (NHL): report of the EORTC randomized phase 3 trial 58951

The European Organisation for Research and Treatment of Cancer 58951 trial for children with acute lymphoblastic leukemia (ALL) or non-Hodgkin lymphoma (NHL) addressed 3 randomized questions, including the evaluation of dexamethasone (DEX) versus prednisolone (PRED) in induction and, for average-ris...

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Veröffentlicht in:	Blood 2010-07, Vol.116 (1), p.36-44
Hauptverfasser:	De Moerloose, Barbara, Suciu, Stefan, Bertrand, Yves, Mazingue, Françoise, Robert, Alain, Uyttebroeck, Anne, Yakouben, Karima, Ferster, Alice, Margueritte, Geneviève, Lutz, Patrick, Munzer, Martine, Sirvent, Nicolas, Norton, Lucilia, Boutard, Patrick, Plantaz, Dominique, Millot, Frederic, Philippet, Pierre, Baila, Liliana, Benoit, Yves, Otten, Jacques
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenal Cortex Hormones - administration & dosage Antineoplastic agents Antineoplastic Combined Chemotherapy Protocols - adverse effects Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biological and medical sciences Chemical and Drug Induced Liver Injury - etiology Chemotherapy Child Child, Preschool Clinical Trials and Observations Dexamethasone - administration & dosage Female Hematologic and hematopoietic diseases Humans Infant Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Lymphoid Neoplasia Lymphoma, Non-Hodgkin - diagnosis Lymphoma, Non-Hodgkin - drug therapy Lymphoma, Non-Hodgkin - mortality Male Medical sciences Osteonecrosis - chemically induced Pharmacology. Drug treatments Precursor Cell Lymphoblastic Leukemia-Lymphoma - diagnosis Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy Precursor Cell Lymphoblastic Leukemia-Lymphoma - mortality Prednisolone - administration & dosage Survival Analysis Survival Rate Treatment Outcome Vincristine - administration & dosage
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