Regulatory RNAs and the HptB/RetS signalling pathways fine-tune Pseudomonas aeruginosa pathogenesis

Bacterial pathogenesis often depends on regulatory networks, two-component systems and small RNAs (sRNAs). In Pseudomonas aeruginosa, the RetS sensor pathway downregulates expression of two sRNAs, rsmY and rsmZ. Consequently, biofilm and the Type Six Secretion System (T6SS) are repressed, whereas th...

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Veröffentlicht in:	Molecular microbiology 2010-06, Vol.76 (6), p.1427-1443
Hauptverfasser:	Bordi, Christophe, Lamy, Marie-Cécile, Ventre, Isabelle, Termine, Elise, Hachani, Abderrahman, Fillet, Sandy, Roche, Béatrice, Bleves, Sophie, Méjean, Vincent, Lazdunski, Andrée, Filloux, Alain
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacterial Proteins - metabolism Bacteriology beta-Galactosidase - metabolism Biofilms Biofilms - growth & development Biological and medical sciences Biological Transport Fundamental and applied biological sciences. Psychology Gene expression Gene Expression Regulation, Bacterial Genes, Reporter Gram-negative bacteria Life Sciences Microbiology Microbiology and Parasitology Miscellaneous Models, Biological Pathogenesis Pseudomonas aeruginosa Pseudomonas aeruginosa - pathogenicity Ribonucleic acid RNA RNA, Bacterial - biosynthesis RNA, Bacterial - genetics RNA, Small Interfering - biosynthesis RNA, Small Interfering - genetics Signal Transduction
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